The first of the animal-research proposals granted permission by the Home Office in 2020, and now published in its non-technical summaries for that year, is a standard ADME project: that is, testing various products for their absorption, distribution, metabolism, and excretion by, in, and from the bodies of live animals. In this case the products are mainly agro-chemicals, and the purpose is to assess “the composition of the terminal residue in the animal products (meat, milk and eggs) that will be consumed by humans”. Administration of the chemicals will be “by injection, dermal application, or gavage [direct into the stomach by tube]”. The ‘dermal application’ is to provide information for “operator exposure assessments”: after all, when you’re out enjoying the fresh air and tending the fields, you want to be well-informed of “your crop-care product’s toxicological profile”. That last phrase is from among the offers of the company Vivotecnia, one of those which provide these ADME services (more about Vivotecnia later).
Most of this type of animal research is done in order to satisfy regulations in the countries where the products are to be used. Such ‘regulatory testing’ accounts for about one quarter of the experimental procedures conducted each year in UK laboratories, and a much higher proportion of the nastiest of them, the so-called ‘severe’ procedures. The practitioners of it are usually the CRO’s (Contract Research Organisations), which gather their work into great 5-year testing projects for Home Office approval, as in the case above. Some of these CRO’s have been founded by vets, putting their expertise to good use. In fact the UK’s Royal Veterinary College (“The world’s leading vet school”) advertises its own CRO facility, providing “large as well as small animal models” for use in “All stages of pre-clinical and clinical product development . . . within the regulatory and non-regulatory environment.” The illustration to go with this offer of ‘Biotechnical Research and Development’ shows men in suits at a reception; this is business, after all, but, reassuringly, it’s “underpinned by the RVC’s reputation for animal welfare” – a fine thing for a veterinary school to have.
But yes, these CRO’s are businesses, and speed and efficiency are what they characteristically promise their clients, rather than the uncertainties and scepticisms of research-science proper or indeed such personal commitment as might go with that. This character of a mass-produced technical service is what the artist Sue Coe suggests with her image of ‘Eden Technologies’ (motto: “Getting it Right from the Start”) in the fiction Pit’s Letter. Eden Technologies! It’s a very well-judged name, being one that’s ever-popular with real biotech businesses or at least their PR agents. In fact only a few weeks ago JHL Biotech (“a global front-runner in biological drug development”) declared itself “excited to announce” a change of name to ‘Eden Biologics’. Sue Coe’s Eden is where Pit, the dog-narrator of the story, has ended up, literally so, along with countless other unfortunate animals. So far from being a Paradise, it’s a hellish place of squalor and cruelty, and indeed Pit says at one point “if we believed in their God, the Devil would look like a human being.” That’s been said before, of course, but some of the more horrifyingly visionary scenes in Pit’s Letter remind us of the many reasons which the twentieth century has provided for saying it yet again (the book was published in 2000). “I walked through past and future, rotten with killing,” says Pit, the ghost who can review it all.
But the grotesque compounding, in Coe’s laboratory scenes, of high technology with filth and slovenly violence, that’s artist’s hyperbole, isn’t it, or at any rate distant history? Apart from anything else, the science would be nearly worthless. Nevertheless, we have to know that it’s both true-to-life and up-to-date. Undercover film, taken between 2018 and 2020 in the Madrid laboratories of Vivotecnia (they of “your crop’s toxicology profile”), has now been published, showing just that same mixture of expensive equipment and physical and moral squalor.
Vivotecnia is a CRO (“researching for you”) that boasts online of its commitment to the “highest standards of animal welfare”. The film shows how little truth there is in that. It’s a sickening thing to watch, rightly classified online as suitable for over-eighteens only. The animals are seen roughly handled, struck, thrown back into their wholly barren cages (“we foster environmental enrichment”, says the Vivotecnia web-site). Individuals are crudely identified with marker pen on forehead or body. Invasive procedures like gavage are conducted with clumsy impatience. Rats are shaken and swung through the air to make them quiescent. There’s blood on the floors. The staff habitually swear at the animals. A background of barking and squealing vocalizes the distress of unseen animals. Worse, there’s deliberate and enjoyed cruelty. Someone draws with marker pen on the genitals of a young monkey being held down for some procedure: “a moustache!” he laughs (the comments of staff are translated in sub-titles). Animals are mocked and taunted, held up for ridicule: “Ha ha ha!” say the sub-titles. It’s scarcely believable, a demonic anarchy.
Vivotecnia is not some rogue company pulled out from the shadows. It was founded in 2000, and is signed up to a whole array of acronymic lab standards and supervisory bodies, both Spanish and international: COSCE, Felasa, OECD, GLP (Good Laboratory Practice!), and of course EU 2010/63. It’s right in the middle of the contract research scene. Therefore Vivotecnia’s disgrace – for even in the few days since the film was released, the public and official response is certain to ruin it – also discredits all those worthy institutional controllers and protectors of this sort of vivisection. It discredits too all those familiar PR phrases about “state of the art facilities”, “paramount” concern for animal well-being, and “highly qualified” management teams (to use more of Vivotecnia’s examples). The whole collective has had a fall and deserved it. For the truth is that forcing animals to take our risks for us like this, in whatever scientific manner, cannot be done ‘humanely’. It necessarily calls out the worst in human beings. It’s incompatible with human decency to do it or to profit from it in any way.
The film has been published online, with an English commentary, by Cruelty Free International, which also sponsors a petition for the closure of Vivotecnia (at present the company’s licence to trade has been suspended). Please sign it! Both film and petition can be seen here: https://crueltyfreeinternational.org/what-we-do/investigations/toxicity-testing-animals-vivotecnia-spain. Please also note that there are other petitions against animal research on the facebook page of World Day for Animals in Laboratories, as well as information about this year’s events, such of them as are possible, on Saturday 24 April.
Notes and references:
Volume 1 of the Home Office’s Non-technical summaries granted in 2020, published in December, has 235 entries, the first being the one described above. The collection can be viewed here: https://www.gov.uk/government/publications/non-technical-summaries-granted-in-2020
The Royal Veterinary College (not to be confused with the Royal College of Veterinary Surgeons, an organisation which really does promote and pioneer animal interests) is quoted from its web-site, in particular the pages about contract work: https://www.rvc.ac.uk/business/services-and-facilities/contract-research-services
Pit’s Letter, by the artist Sue Coe, was published in 2000 by Four Walls Eight Windows.
The Vivotecnia web-site (https://www.vivotecnia.com/about-us/), from which the quotations were taken, is now unavailable, owing to “maintenance”.
The Guardian has featured the exposure in two articles, this month, both available to read online: on 8 April at https://www.theguardian.com/environment/2021/apr/08/undercover-footage-shows-gratuitous-cruelty-at-spanish-animal-testing-facility-madrid-vivotecnia, and 12 April at https://www.theguardian.com/environment/2021/apr/12/animal-testing-suspended-at-spanish-lab-after-gratuitous-cruelty-footage